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Small ubiquitin-related modifier 1
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Small ubiquitin-related modifier 1 : ウィキペディア英語版
Small ubiquitin-related modifier 1

Small ubiquitin-related modifier 1 is a protein that in humans is encoded by the ''SUMO1'' gene.

Most cleft genes have a sumoylation component . Analysis of chromosomal anomalies in patients has led to the identification and confirmation of SUMO1 as a cleft lip and palate locus.〔Dixon MJ, Marazita ML, Beaty TH, Murray JC (2011). "Cleft lip and palate: understanding genetic and environmental influences". ''Nature Reviews Genetics'' (12) 167-178.〕
==Interactions==
Small ubiquitin-related modifier 1 has been shown to interact with SAE2, Death-associated protein 6, Fas receptor,〔 Sp1 transcription factor, PIAS1, Thymine-DNA glycosylase, UBE2I,〔〔 TNFRSF1A,〔 P53,〔〔 TOP2B, TOP2A,〔 DNMT3B, Promyelocytic leukemia protein,〔 and C22orf25.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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